Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Solid Tumor Cancers With KRAS G12V Mutations
PHASE1
This phase I trial studies the side effects and best dose of autologous CD8...
Status
Recruiting
Location
Fred Hutch/University of Washington Cancer Consortium
Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy
PHASE2
This phase II/III trial studies how well daunorubicin and cytarabine with o...
XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue Sarcoma
PHASE2
This phase II trial tests how well zanzalintinib (XL092) works in treating ...
Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers
PHASE2
This phase II trial compares the effect of usual treatment of docetaxel che...
Venetoclax in Combination With Cladribine and Cytarabine Alternating With Azacitidine Plus Venetoclax for the Treatment of Newly Diagnosed Monocytic AML and Active Signaling Mutated AML
PHASE2
This phase II trial tests how well venetoclax with cladribine and cytarabin...
Status
Recruiting
Location
University of Miami Miller School of Medicine-Sylvester Cancer Center
Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma
PHASE1
This phase I trial tests the safety and side effects of B-cell activating f...
Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse
PHASE1
This phase I/II trial studies the safety, side effects, and best dose of de...
Status
Recruiting
Location
Fred Hutch/University of Washington Cancer Consortium